Effects of ketamine on cognition-emotion interaction in the brain
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- 作者：Milan Scheideggera ; b ; scheidegger@biomed.ee.ethz.ch" class="auth_mail" title="E-mail the corresponding author ; Anke Henninga ; f ; Martin Walterc ; d ; Heinz Boekerb ; Anne Weigande ; Erich Seifritzb ; f ; Simone Grimmb ; e
- 关键词：Ketamine ; Cognition&ndash ; emotion interaction ; Working memory
- 刊名：NeuroImage
- 出版年：2016
- 出版时间：1 January 2016
- 年：2016
- 卷：124
- 期：part_PA
- 页码：8-15
- 全文大小：548 K
文摘
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Ketamine modulates cognition–emotion interaction during a working memory fMRI task.
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In cortical midline regions ketamine abolishes enhancement of deactivation.
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Right DLPFC and left insula activation is reduced for negative stimuli by ketamine.
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Effects of ketamine depend on emotional content and emotional valence.
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Less interference of negative-biased cognition might be antidepressant.