Amine bridges grafted mesoporous silica, as a prolonged/controlled drug release system for the enhanced therapeutic effect of short life drugs

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• 作者：Fozia Rehman^a ; ^b ; ^{foziaics@yahoo.com} ; Khalid Ahmed^a ; Claudio Airoldi^a ; Simon Gaisford^c ; Asma Buanz^c ; Abdur Rahim^b ; Nawshad Muhammad^b ; Pedro L.O. Volpe^a
• 关键词：Mesoporous silica ; Surface modification ; Ibuprofen and controlled drug release
• 刊名：Materials Science and Engineering: C
• 出版年：2017
• 出版时间：1 March 2017
• 年：2017
• 卷：72
• 期：Complete
• 页码：34-41
• 全文大小：997 K
• 卷排序：72

文摘

Silica SBA-15 was synthesized and modified with long hydrophobic amine linkers. These materials were characterized using different techniques. The modified material showed high drug loading capacity and control ibuprofen release in biological fluids.