Immunomodulatory activity of protein hydrolysates derived from Virgibacillus halodenitrificans SK1-3-7 proteinase

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• 作者：Tidarat Toopcham^a ; Jurriaan J. Mes^b ; Harry J. Wichers^b ; ^{harry.wichers@wur.nl} ; Jirawat Yongsawatdigul^a ; ^{jirawat@sut.ac.th}
• 关键词：Protein hydrolysate ; Macrophages ; Immunomodulation ; Inflammation
• 刊名：Food Chemistry
• 出版年：2017
• 出版时间：1 June 2017
• 年：2017
• 卷：224
• 期：Complete
• 页码：320-328
• 全文大小：1579 K
• 卷排序：224

文摘

Hydrolysates from tilapia, casein, and pea, exhibit immunomodulatory activity. Tilapia hydrolysate enhances innate immunity by promoting IL-1β and COX-2. Casein and pea hydrolysates suppress LPS-induced pro-inflammatory gene expression. Hydrolysates exhibit stronger anti-inflammatory activity than intact proteins.