Laboratory assessment and diagnosis of congenital viral infections: Rubella, cytomegalovirus (CMV), varicella-zoster virus (VZV), herpes simplex virus (HSV), parvovirus B19 and human immunodeficiency

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• 作者：Ella Mendelson ; Yair Aboudy ; Zahava Smetana ; Michal Tepperberg and Zahava Grossman
• 关键词：Laboratory diagnosis ; Congenital viral infections ; Rubella ; Cytomegalovirus (CMV) ; Varicella-zoster virus (VZV) ; Herpes simplex virus (HSV) ; Parvovirus B19 ; Human immunodeficiency virus (HIV)
• 刊名：Reproductive Toxicology
• 出版年：2006
• 出版时间：May 2006
• 年：2006
• 卷：21
• 期：4
• 页码：350-382
• 全文大小：696 K

文摘

Viral infections during pregnancy may cause fetal or neonatal damage. Clinical intervention, which is required for certain viral infections, relies on laboratory tests performed during pregnancy and at the neonatal stage. This review describes traditional and advanced laboratory approaches and testing methods used for assessment of the six most significant viral infections during pregnancy: rubella virus (RV), cytomegalovirus (CMV), varicella-zoster virus (VZV), herpes simplex virus (HSV), parvovirus B19 and human immunodeficiency virus (HIV). Interpretation of the laboratory tests results according to studies published in recent years is discussed.