Pap cytopathology and the presence of high-risk human papillomavirus in SurePath™ liquid preservative and Digene cervical sampler specimens

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• 作者：Julius Kapala ; Dan Jang ; Jay Patel ; Kathleen Biers ; Marek Smieja ; Max Chernesky
• 关键词：Hybrid Capture 2 ; High-risk HPV ; SurePath liquid Pap ; Cytopathology
• 刊名：Journal of Virological Methods
• 出版年：2007
• 出版时间：June 2007
• 年：2007
• 卷：142
• 期：1-2
• 页码：223-225
• 全文大小：111 K

文摘

The Digene Hybrid Capture 2 (HC2) assay for high-risk human papillomavirus (HPV) identified 92 (28.7 % ) infected women by testing 320 SurePath liquid-based Pap samples and a hybrid capture 2 (HC2) sampler collection. HPV positivity was predictive for high-grade lesions. A majority of women had normal cervical readings although 15.8 % were HPV-positive. Half of the patients with a reading of atypical squamous cells of undetermined significance (ASCUS) (n = 16) were HPV-positive.