Preparation of perovskite-type composite oxide LaNi_0.5Ti_0.5O₃¨CNiFe₂O₄ and its application in glucose biosensor

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• 作者：Yulong Wang^a ; Yanhong Xu^b ; Liqiang Luo^a ; Yaping Ding^a ; ^b ; ^{wdingyp@sina.com} ; Xiaojuan Liu^a
• 关键词：Perovskite-type ; Biosensor ; Carbon paste electrode ; Glucose oxidase
• 刊名：Journal of Electroanalytical Chemistry
• 出版年：2010
• 出版时间：1 April 2010
• 年：2010
• 卷：642
• 期：1
• 页码：35-40
• 全文大小：1050 K

文摘

A novel nanostructured perovskite-type composite oxide LaNi_0.5Ti_0.5O₃¨CNiFe₂O₄ (LNT¨CNFO) was synthesized by sol¨Cgel method and characterized by X-ray diffractometer (XRD) and transmission electron microscopy (TEM). Amperometric glucose biosensors based on the carbon paste electrode (CPE) were constructed by immobilizing glucose oxidase (GOD) with LNT¨CNFO and the experimental conditions such as the amount of GOD, pH value, and applied potential were investigated. Under the optimum conditions, the electrochemical performances of the LNT¨CNFO with different ratios of LNT-NFO (10:1, 20:1, 30:1) modified CPE have been researched on the oxidation of glucose. The results show that LNT¨CNFO (20:1) can immobilize GOD more effectively. The biosensor based on LNT¨CNFO/CS/GOD modified CPE exhibits good reproducibility, stability and selectivity in glucose determination with linear signal-to-glucose concentration range of 0.5?0 mM and a detection limit (S/N = 3) of 0.04 mM.