Modeling autism spectrum disorders with human neurons

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• 作者：Patricia C.B. Beltrã ; o-Braga^a ; ^b ; ^c ; ^d ; ^{patriciacbbbraga@usp.br} ; Alysson R. Muotri^b ; ^{muotri@ucsd.edu}
• 关键词：Autism spectrum disorders ; Disease modeling ; Human induced pluripotent stem cells ; Human neurons
• 刊名：Brain Research
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：1656
• 期：Complete
• 页码：49-54
• 全文大小：309 K
• 卷排序：1656

文摘

A new human model to study autism spectrum disorders. Advances on modeling monogenetic autisms. Efforts on modeling rare variants related to autism. The use of induced pluripotent stem cells derived neurons for drug screening.