Multi-scale analysis of neural activity in humans: Implications for micro-scale electrocorticography
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- 作者：Spencer Kellisa ; 1 ; Larry Sorensene ; Felix Darvasf ; Conor Sayresf ; Kevin O&rsquo ; Neill IIIh ; Richard B. Browna ; b ; d ; Paul Housec ; Jeff Ojemannf ; g ; Bradley Gregerh ; bradley.greger@asu.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Brain computer interface (BCI) ; Human cerebral cortex ; Micro-electrocorticography grid ; Neural engineering ; Neural microtechnology
- 刊名：Clinical Neurophysiology
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：127
- 期：1
- 页码：591-601
- 全文大小：1660 K
文摘
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We recorded neural activity using standard clinical ECoG grids, micro-ECoG grids, and intracortical micro-electrodes from human patients.
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We found that non-penetrating micro-ECoG grid recorded neural activity at scales closer to penetrating intracortical micro-electrodes than clinical ECoG grids.
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These novel micro-electrode technologies are enabling examination of cortical activity at the scale of cortical columns and could lead to improved diagnostics and neural prosthetic applications.