Astrocytes contribute to the effects of etomidate on synaptic transmission in rat primary somatosensory cortex
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- 作者：Hao Yanga ; Yuan Wanga ; b ; Yu Zhanga ; b ; You Zhanga ; Mao-sheng Xua ; Jie Yuana ; Tian Yua ; b ; yutianzymc@sina.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：ACSF ; artificial cerebrospinal fluid ; AP5 ; D ; L-2-amino-5-phosphonovaleric acid ; DNQX ; 6 ; 7-dinitroquinoxaline-2 ; 3-dione ; EC50 ; the concentration for 50% of maximal effect ; EGTA ; ethylene glycol tetraacetic acid ; HEPES ; 4-(2-hydroxyethyl)&minus ; 1-piperazineethanesulfonic acid ; sPSCs ; spontaneous postsynaptic currents ; TTX ; tetrodotoxin
- 刊名：Brain Research
- 出版年：2016
- 出版时间：1 July 2016
- 年：2016
- 卷：1642
- 期：Complete
- 页码：238-243
- 全文大小：1751 K
文摘
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Etomidate suppresses synaptic activity via pre- and post-synaptic components.
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Astrocytes participate in and modulate synaptic transmission.
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Astrocytes influence the effects of etomidate on postsynaptic receptors in rat S1.