Oral fluid cocaine and benzoylecgonine concentrations following controlled intravenous cocaine administration
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- 作者：Kayla N. Ellefsena ; b ; Marta Concheiroc ; Sandrine Pirarda ; David A. Gorelickd ; Marilyn A. Huestisa ; mhuestis@intra.nida.nih.gov" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cocaine ; Benzoylecgonine ; Oral Fluid ; Oral-Eze® ; Pharmacokinetics ; StatSure Saliva Sampler&trade
- 刊名：Forensic Science International
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：260
- 期：Complete
- 页码：95-101
- 全文大小：655 K
文摘
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Oral fluid (OF) pharmacokinetic data after intravenous cocaine are presented.
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Oral-Eze and StatSure OF collection device performance was evaluated.
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Oral-Eze had significantly longer cocaine OF T1/2 (1.3 h) than StatSure (0.89 h).
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Oral-Eze and StatSure devices were effective in monitoring cocaine and BE in OF.
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Cocaine and BE confirmatory cutoffs can be selected to meet drug testing needs.