Applying 3D-FRAP microscopy to analyse gap junction-dependent shuttling of small antisense RNAs between cardiomyocytes
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- 作者：Heiko Lemcke ; heiko.lemcke@uni-rostock.de" class="auth_mail" title="E-mail the corresponding author ; Janine Peukert ; Natalia Voronina ; Anna Skorska ; Gustav Steinhoff ; Robert David ; robert.david@med.uni-rostock.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：miRNA transfer ; Gap junctions ; Connexins ; Small noncoding RNA ; Intercellular communication ; Neonatal cardiomyocytes
- 刊名：Journal of Molecular and Cellular Cardiology
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：98
- 期：Complete
- 页码：117-127
- 全文大小：2511 K
文摘
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small non coding RNAs are transferred between cardiomyocytes
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3-dimensional FRAP microscopy was used to visualise the rapid gap junctional shuttling of miRNA in single cells
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3-dimensional FRAP microscopy is superior to 2D applications when studying gap junction dependent miRNA transfer