Crystal Structures of the Extracellular Domain from PepT1 and PepT2 Provide Novel Insights into Mammalian Peptide Transport
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- 作者：John H. Beale1 ; 10 ; Joanne L. Parker1 ; 10 ; Firdaus Samsudin1 ; 10 ; Anne L. Barrett1 ; 2 ; Anish Senan3 ; Louise E. Bird4 ; 5 ; David Scott6 ; 7 ; 8 ; Raymond J. Owens4 ; 5 ; Mark S.P. Sansom1 ; 9 ; Stephen J. Tucker2 ; 9 ; David Meredith4 ; Philip W. Fowler1 ; Simon Newstead1 ; 9 ; simon.newstead@bioch.ox.ac.uk" class="auth_mail" title="E-mail the corresponding author
- 刊名：Structure
- 出版年：2015
- 出版时间：6 October 2015
- 年：2015
- 卷：23
- 期：10
- 页码：1889-1899
- 全文大小：2715 K
文摘
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Crystal structure of the extracellular domains of PepT1 and PepT2
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Modular architecture for a mammalian MFS transporter
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Extracellular domains contain immunoglobulin-like fold and interact with trypsin