Highlights of a workshop to discuss targeting inflammation in cystic fibrosis

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• 作者：Katharine H. Banner ; Hugo De Jonge ; Stuart Elborn ; Ellena Growcott ; Erich Gulbins ; Mike Konstan ; Rick Moss ; Chris Poll ; Scott H. R ; ell ; Adriano G. Rossi ; Lorraine Thomas ; David Waltz
• 关键词：Cystic fibrosis ; Inflamation ; Neutrophil ; Lymphocyte ; Epithelial cell
• 刊名：Journal of Cystic Fibrosis
• 出版年：2009
• 出版时间：January 2009
• 年：2009
• 卷：8
• 期：1
• 页码：1-8
• 全文大小：602 K

文摘

A workshop to discuss anti-inflammatory approaches in the treatment of CF was held at Novartis Institutes for Biomedical Research (NIBR, Horsham, UK) in March 2008.

Key opinion leaders in the field (Hugo De Jonge, Stuart Elborn, Erich Gulbins, Mike Konstan, Rick Moss, Scott Randell and Adriano Rossi), and NIBR scientists were brought together to collectively address three main aims: (i) to identify anti-inflammatory targets in CF, (ii) to evaluate the pros and cons of targeting specific cell types and (iii) to discuss model systems to profile potential therapeutic agents.

The highlights of the workshop are captured in this review.