Polycistronic trypanosome mRNAs are a target for the exosome
详细信息 查看全文
- 作者：Susanne Kramera ; b ; susanne.kramer@uni-wuerzburg.de" class="auth_mail" title="E-mail the corresponding author ; Sophie Piperb ; Antonio Estevezc ; Mark Carringtonb
- 关键词：Trypanosoma brucei ; Exosome ; NMD ; Polycistronic mRNA ; trans-splicing ; Trypanosomes
- 刊名：Molecular & Biochemical Parasitology
- 出版年：2016
- 出版时间：January-February 2016
- 年：2016
- 卷：205
- 期：1-2
- 页码：1-5
- 全文大小：1296 K
文摘
- •
RNAi depletion of exosomal subunits causes accumulation of oligocistronic mRNAs.
- •
RNAi depletion of the 5′-3′ exoribonuclease XRNA or UPF1 has no effect on oligocistronic mRNAs.
- •
eYFP fusions of the exosome subunits RRP44 and RRP6 localize to the nucleus.