Antibacterial Activity of Thai Medicinal Plants against Methicillin-resistant Staphylococcus aureus

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• 作者：Mullika Traidej Chomnawang ; Suvimol Surassmo ; Karn Wongsariya ; Nuntavan Bunyapraphatsara
• 关键词：Methicillin-resistant S. aureus ; Medicinal plants ; Antibacterial activity ; Bioautography ; Garcinia mangostana ; α ; -mangostin
• 刊名：Fitoterapia
• 出版年：2009
• 出版时间：March 2009
• 年：2009
• 卷：80
• 期：2
• 页码：102-104
• 全文大小：161 K

文摘

Methicillin-resistant Staphylococcus aureus (MRSA) is a major nosocomial pathogen which causes severe morbidity and mortality worldwide. Seventeen Thai medicinal plants were investigated for their activity against MRSA. Garcinia mangostana was identified as the most potent plant, and its activity was traced to the prenylated xanthone, α-mangostin (MIC and MBC values of 1.95 and 3.91 µg/ml, respectively).