Exposure to household air pollution (HAP) has been linked to systemic inflammation. Determined impact of transition from traditional firewood/kerosene fuel to ethanol on inflammatory biomarkers in pregnant Nigerian women. Decrease in TNF-α from first to third trimesters in intervention group could indicate reduced cardiovascular stress and prothrombotic effects. Ethanol-burning stoves may mitigate cardiovascular health risks. Switching to ethanol-based stoves provides much-needed hope for a sustainable cooking alternative to unclean fuels in countries like Nigeria. This study has public and global health implication, supports and reiterates the need to follow WHO guidelines for indoor air quality.