The network of causal interactions for beta oscillations in the pedunculopontine nucleus, primary motor cortex, and subthalamic nucleus of walking parkinsonian rats
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- 作者：Min Lia ; Ming Zhoua ; Peng Wena ; Qiang Wanga ; Yong Yanga ; Hu Xiaoa ; Zhengyuan Xiea ; Xing Lib ; Ning Wangc ; Jinyan Wangc ; Fei Luoc ; Jingyu Changd ; Wangming Zhanga ; wzhang@vip.126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Parkinson's disease ; Parkinsonian rats ; Local field potentials ; Beta band oscillations ; Pedunculopontine nucleus ; Primary motor cortex ; Subthalamic nucleus
- 刊名：Experimental Neurology
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：282
- 期：Complete
- 页码：27-36
- 全文大小：1798 K
文摘
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After 6-OHDA lesions, beta band oscillations were enhanced in all three regions during walking.
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The direction of information flow for beta oscillations among three structures was STN → M1, STN → PPN, and PPN → M1.
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Beta activity in the PPN is transmitted from the basal ganglia and probably comes from the STN.
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The STN may be a potential source of aberrant beta band oscillations in PD.
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Beta oscillations may not be the major cause of axial symptoms.