An alternative total synthesis of bolivianine

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• 作者：Jin-Peng Li ; Chang-Chun Yuan ; Biao Du ; Bo Liu ; ^{chembliu@scu.edu.cn}
• 关键词：Total synthesis ; Cyclopropanation ; Aldol ; Diels-Alder ; Terpeniod
• 刊名：Chinese Chemical Letters
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：28
• 期：1
• 页码：113-116
• 全文大小：632 K
• 卷排序：28

文摘

An alternative total synthesis of bolivianine in twelve steps is herein reported on the basis of our previous successful bioinspired total synthesis. The present total synthesis features straightforward transformation from an aldol product to the butenolide of the target molecule, and stereoselective Diels-Alder cycloaddition to construct ring E, as well as the final spontaneous IMHDA process.