We evaluate MVCT RSP-to-HU calibration against kVCT calibration for proton therapy.
Use image registration to enable comparison between CT calibrations on patient data.
MVCT and kVCT calibrations yield consistent RSP for soft tissue except adipose.
MVCT and kVCT calibrations yield inconsistent RSP for boney structures and adipose.
Uncertainty analysis and clinical study showed RSP difference may have clinical impact.