Semen and hormonal parameters in men with chronic hepatitis C infection

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• 作者：Eman Riaad M. Hofny ; Mohammed Essam M. Ali ; Emad A. Taha ; Hanan M. Nafeh ; Doaa Samir Sayed ; Hanan G. Abdel-Azeem ; Ehab Fawzy Abdou ; Ghada Mostafa Kamal ; Taymour Mostafa
• 关键词：Hepatitis ; HCV ; semen ; hormones ; viral load
• 刊名：Fertility and Sterility
• 出版年：2011
• 出版时间：30 June 2011
• 年：2011
• 卷：95
• 期：8
• 页码：2557-2559
• 全文大小：78 K

文摘

Male patients with chronic hepatitis C virus (HCV) infection (n = 57) demonstrated a statistically significant decrease in semen volume, sperm count, and progressive sperm motility and a statistically significant increase in abnormal sperm morphology compared with healthy controls (n = 40). The duration of the HCV infection was negatively correlated with semen volume and sperm motility where the HCV RNA viral load was negatively correlated with sperm count and sperm motility. Chronic HCV patients had statistically significantly lower total serum testosterone and higher serum E₂ and prolactin levels compared with healthy controls.