0417 : Thrombolisis with tenecteplase (metalyse) in myocardial infarction an always topical issue

详细信息    查看全文

• 作者：A. Belouaer ; ^{belouaeramina@yahoo.fr" class="auth_mail" title="E-mail the corresponding author} ; T. Boukadida ; R. Gheni ; R. Ben Hmida ; I. Rachikou ; T. Ounissi ; N. Barakett
• 刊名：Archives of Cardiovascular Diseases Supplements
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：8
• 期：3
• 页码：206-207
• 全文大小：52 K

文摘

ST elevated myocardial infraction (STEMI) is a common disease, which currently represents a public health problem affecting increasingly young people. Moreover, it is not always easy to access to the transluminal coronary angioplasty (TCA) therefore the importance of thrombolysis. The aim of this study was the evaluation of myocardial infraction thrombolysis by tenecteplase (Metalyse*) and to highlight the experience of a Cardiology department Nabeul's cardiology departement a local cardiology departement in Tunisia in case of STEMI.

Methods

During the study period from July 2011 to December 2013, 104 patients were hospitalized in the cardiology department of Nabeul's hopital for STEMI and thrombolysed with Metalyse.

Results

104 patients had a confirmed diagnosis and had a tenecteplase thrombolysis. The average age of our patients was 55 years with a sex ratio of 8,45. The most common risk factor was tobacco. The average time between start of chest pain and admission in hospital was 4,12 hours. Two third of patients consulted in 5 hours. The average success rate of thrombolysis was 89% and 92% during the first 3 hours and 84% beyond the sixth hour. One patient had a bleeding complication postthrombolysis (CVA). Six deaths were © Elsevier Masson SAS. All rights reserved. recorded in relation to: cardiogenic shock (3 cases), asystole occurred following an unreduced by EEC FV (2 cases) and hemorrhagic stroke (1 case).

Conclusion

Thrombolysis by Tenecteplase of STEMI admitted to ICCU was successfull in 89% of cases, which proves its effectiveness compared with other thrombolytic agents. The reperfusion rate was inversely proportional to time limit chest pain – arrival at ER. Patient education to call the ambulance (190) in case of chest pain should improve this delay and increase the reperfusion rate.

The author hereby declares no conflict of interest