Adipose-derived stem cells ameliorate renal interstitial fibrosis through inhibition of EMT and inflammatory response via TGF-β1 signaling pathway

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• 作者：Yan Song^a ; Changliang Peng^b ; Shasha Lv^a ; Jing Cheng^a ; Shanshan Liu^a ; Qing Wen^a ; Guangju Guan^a ; ¹ ; ^{guangj@sdu.edu.cn} ; Gang Liu^a ; ¹ ; ^{lg69007@163.com}
• 关键词：ADSCs ; Renal interstitial fibrosis ; EMT ; Inflammatory response ; TGF-β1
• 刊名：International Immunopharmacology
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：44
• 期：Complete
• 页码：115-122
• 全文大小：1656 K
• 卷排序：44

文摘

ADSCs significantly ameliorate renal interstitial fibrosis. ADSCs significantly attenuate EMT and inflammatory response. Mechanism is via inhibition of the activation of TGF-β1 signaling pathway.