The BB2 receptor antagonist BW2258U89 attenuates the feeding responses evoked by exogenous gastrin releasing peptide-29
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- 作者：Martha C. Washington ; Thaer R. Mhalhal ; Ayman I. Sayegh ; sayeghai@mytu.tuskegee.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：GRP ; Meal size ; Intermeal interval ; Satiety ratio ; Celiac artery
- 刊名：Hormones and Behavior
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：85
- 期：Complete
- 页码：1-4
- 全文大小：364 K
文摘
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Gastrin releasing peptide-29 (GRP-29) is the large molecular form of GRP in the rat.
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GRP-29 reduces meal size (MS) and prolongs the intermeal interval (IMI).
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The BB2 receptor is necessary for MS reduction and IMI prolongation by GRP-29.
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The celiac artery supplies sites of action controlling MS and IMI by GRP-29.