Subthalamic nucleus involvement in children: A聽neuroimaging pattern-recognition approach

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• 作者：Thangamadhan Bosemani^a ; Cristina Anghelescu^b ; Eugen Boltshauser^c ; Alexander H. Hoon Jr.^d ; ^e ; Phillip L. Pearl^f ; Dana Craiu^b ; ^g ; Michael V. Johnston^d ; ^e ; ^h ; Thierry A.G.M. Huisman^a ; Andrea Poretti^a ; ^c ; ^{aporett1@jhmi.edu" class="auth_mail}
• 关键词：Magnetic resonance imaging ; Pattern-recognition approach ; Subthalamic nucleus ; Children
• 刊名：European Journal of Paediatric Neurology
• 出版年：May 2014
• 年：2014
• 卷：18
• 期：3
• 页码：249-256
• 全文大小：1554 K

文摘

A neuroimaging-based pattern-recognition approach has been shown to be very helpful in the diagnosis of a wide range of pediatric central nervous system diseases. Few disorders may selectively affect the subthalamic nucleus in children including Leigh syndrome, succinic semialdehyde dehydrogenase deficiency, kernicterus, chronic end-stage liver failure and near total hypoxic-ischemic injury in the full-term neonates. The consideration of the constellation of clinical history and findings as well as additional neuroimaging findings should allow planning the appropriate diagnostic tests to make the correct diagnosis in children with involvement of the subthalamic nucleus.