Chitosan-coated poly(lactic-co-glycolic acid) perfluorooctyl bromide nanoparticles for cell labeling in 19F magnetic resonance imaging
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- 作者：Hieu Vu-Quanga ; b ; d ; Mads Sloth Vindinga ; c ; Dan Xiaa ; Thomas Nielsena ; c ; Marcus Gö ; rge Ullischa ; c ; MingDong Donga ; Niels Chr. Nielsena ; b ; c ; d ; Jø ; rgen Kjemsa ; b ; c ; e ; jk@mb.au.dk" class="auth_mail" title="E-mail the corresponding author
- 关键词：19F-MRI ; PLGA ; PFOB ; Chitosan
- 刊名：Carbohydrate Polymers
- 出版年：2016
- 出版时间：20 January 2016
- 年：2016
- 卷：136
- 期：Complete
- 页码：936-944
- 全文大小：2445 K
文摘
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We aim to make an efficient cell labeling agent for 19F-MRI.
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19F-MRI is an advantageous imaging technique to obtain the images with background free.
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By adjusting the weight ratio between chitosan and nanoparticle, we could achieve the best cell labeling efficiency.
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Cell after labeling could be monitored using 19F-MRI.