Electron Transport Chain Remodeling by GSK3 during Oogenesis Connects Nutrient State to Reproduction
详细信息 查看全文
- 作者：Matthew H. Sieber1 ; Michael B. Thomsen2 ; Allan C. Spradling1 ; 3 ; spradling@ciwemb.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell
- 出版年：2016
- 出版时间：28 January 2016
- 年：2016
- 卷：164
- 期：3
- 页码：420-432
- 全文大小：3073 K
文摘
- <dt class="label">•dt>
A shift in carbohydrate catabolism promotes glycogen accumulation during oogenesis
<dt class="label">•dt>Oocyte mitochondria enter a low-activity state by remodeling respiratory complexes
<dt class="label">•dt>Loss of AKT activity during late oogenesis stimulates GSK3 to remodel the ETC
<dt class="label">•dt>ETC remodeling is the result of a shift in mitochondrial protein content