Anti-inflammatory effects of the essential oils of ginger (Zingiber officinale Roscoe) in experimental rheumatoid arthritis
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- 作者：Janet L. Funka ; jfunk@u.arizona.edu" class="auth_mail" title="E-mail the corresponding author ; Jennifer B. Fryea ; jabeisch@u.arizona.edu" class="auth_mail" title="E-mail the corresponding author ; Janice N. Oyarzoa ; joyarzo@email.arizona.edu" class="auth_mail" title="E-mail the corresponding author ; Jianling Chena ; chenjianliang05@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Huaping Zhangb ; hankzhang@ku.edu" class="auth_mail" title="E-mail the corresponding author ; Barbara N. Timmermannb ; btimmer@ku.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：17 beta estradiol (PubChem CID ; 5757) ; 6-Gingerol (PubChem CID ; CID ; 442793) ; Geranial (PubChem CID ; 638011) ; Neral (PubChem CID ; 643779)
- 刊名：PharmaNutrition
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：4
- 期：3
- 页码：123-131
- 全文大小：2140 K
文摘
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While anti-inflammatory effects of ginger are often attributed to its gingerols, each of its secondary metabolites, the essential oils and the gingerols, are joint protective in an experimental arthritis model.
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Both of ginger’s secondary metabolites (essential oils and gingerols) have anti-arthritic effects in an experimental model.
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Anti-arthritic effects of ginger essential oils (GEO) mirrored those of 17-β estradiol.
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However, GEO had no effect on classic estrogen-responsive organs.
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GEO were well tolerated.
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GEO and gingerols may have additive joint protective effects in arthritis.