Tomato cystine-knot miniproteins possessing anti-angiogenic activity exhibit in vitro gastrointestinal stability, intestinal absorption and resistance to food industrial processing

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• 作者：Davide Treggiari^a ; ^b ; ^{davide.treggiari@univr.it} ; Gianni Zoccatelli^a ; ^{gianni.zoccatelli@univr.it} ; Roberto Chignola^a ; ^{roberto.chignola@univr.it} ; Barbara Molesini^a ; ^{barbara.molesini@univr.it} ; Pietro Minuz^b ; ^{pietro.minuz@univr.it} ; Tiziana Pandolfini^a ; ^{tiziana.pandolfini@univr.it}
• 关键词：Cystine-knot miniproteins ; Endothelial cell migration ; Gastrointestinal digestion ; Intestinal transport ; Tomato paste
• 刊名：Food Chemistry
• 出版年：2017
• 出版时间：15 April 2017
• 年：2017
• 卷：221
• 期：Complete
• 页码：1346-1353
• 全文大小：894 K
• 卷排序：221

文摘

Tomato cysteine-rich miniproteins (TCMPs) possess anti-angiogenic properties. TCMPs are resistant to gastrointestinal peptidases and actively cross the intestinal mucosa. The industrial processing does not modified TCMPs’ biological activities.