G9a inhibition promotes neuronal differentiation of human bone marrow mesenchymal stem cells through the transcriptional induction of RE-1 containing neuronal specific genes
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- 作者：Ho-Tae Kima ; b ; Sin-Gu Jeonga ; b ; Goang-Won Choa ; b ; gwcho@chosun.ac.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：G9a ; RE-1 (repressor element-1) ; REST (RE-1 silencing transcription factor) ; Neuronal differentiation ; BIX01294 ; Bone marrow mesenchymal stem cells (BM-MSCs)
- 刊名：Neurochemistry International
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：96
- 期：Complete
- 页码：77-83
- 全文大小：1063 K
文摘
- 10">
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10">Inhibition of G9a causes increased expression of neuronal marker genes.
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15">BIX01294 treatment improves the rate of neuronal differentiation in hBM-MSCS.
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BIX01294 promotes neuronal differentiation via expression of RE-1 containing genes.