Apigenin protects myocardium by inhibiting the TGF-β₁-mediated Smad signaling transduction pathway in acute myocardial infarcted rats

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• 作者：Ziliang Wang^a ; ^b ; Yan Chen^c ; Dingli Xu^a ; ^{dinglixu@smu.edu.cn}
• 关键词：AMI ; Apigenin ; TGF-β1 signaling ; Smad 7
• 刊名：Journal of Functional Foods
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：30
• 期：Complete
• 页码：48-55
• 全文大小：2856 K
• 卷排序：30

文摘

Apigenin improves the function and structure of AMI injured cardiomyocytes. Expressions of TGF-β1 and Smad 2 are inhibited by apigenin. Apigenin exerts its effect on cardiomyocytes via TGF-β1/Smad signaling.