Identification of three ookinete-specific genes and evaluation of their transmission-blocking potentials in Plasmodium berghei
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- 作者：Wenqi Zhenga ; Xu Koua ; b ; Yunting Duc ; Fei Liuc ; Chunyun Yuc ; Takafumi Tsuboid ; Qi Fane ; Enjie Luoa ; enjieluo@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Yaming Caoc ; ymcao@mail.cmu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Liwang Cuif
- 关键词：Malaria ; Sexual stage ; Transmission-blocking vaccine ; Plasmodium berghei
- 刊名：Vaccine
- 出版年：2016
- 出版时间：17 May 2016
- 年：2016
- 卷：34
- 期：23
- 页码：2570-2578
- 全文大小：1266 K
文摘
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We mined PlasmoDB and selected three ookinete-specific genes in Plasmodium.
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We confirmed their expression and localization on P. berghei ookinetes.
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Antisera against these recombinant proteins had transmission blocking activity.