Tuft Cells: A New Flavor in Innate Epithelial Immunity

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• 作者：Richard K. Grencis¹ ; ^{richard.grencis@manchester.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; John J. Worthington² ; ^{j.j.worthington@lancaster.ac.uk" class="auth_mail" title="E-mail the corresponding author}
• 刊名：Trends in Parasitology
• 出版年：2016
• 出版时间：August 2016
• 年：2016
• 卷：32
• 期：8
• 页码：583-585
• 全文大小：5724 K

文摘

How host cells sense intestinal parasitic infection and initiate the appropriate immune response has long been a focus of many immunologists. Three new papers now identify a critical role for tuft cells, an epithelial cell type involved in perception of taste, as key players that kick-start type 2 immunity.