Consecutive 21 patients with status migrainosus were received intra-venous chlorpromazine (maximum 25 mg) with fluid treatment and their results were documented.
Complete recovery of headache and nausea were seen in 20/21 and 17/21 of the patients respectively. 15/21 of patients were headache free following at 10 mg chlorpromazine infusion. Most patients went on sleep after 10 mg chlorpromazine infusion and when they wake already up headache free. Side effects such as tachycardia, palpitation, flushing and hypertension were seen only one of 21 patients following first dose 5 mg injection.
This study showed that intra-venous chlorpromazine with fluid treatment for status migrainosus seems a good option.