A community based primary prevention programme for type 2 diabetes integrating identification and lifestyle intervention for prevention: the Let's Prevent Diabetes cluster randomised controlled trial
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- 作者：Melanie J. Daviesa ; b ; melanie.davies@uhl-tr.nhs.uk" class="auth_mail" title="E-mail the corresponding author ; Laura J. Grayc ; lg48@le.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Jacqui Troughtond ; Jacqui.Troughton@uhl-tr.nhs.uk" class="auth_mail" title="E-mail the corresponding author ; Alastair Graye ; alastair.gray@dph.ox.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Jaakko Tuomilehtof ; g ; h ; jaakko.tuomilehto@thl.fi" class="auth_mail" title="E-mail the corresponding author ; Azhar Farooqia ; azhar_farooqi@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Kamlesh Khuntia ; kk22@le.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Thomas Yatesa ; b ; ty20@le.ac.uk" class="auth_mail" title="E-mail the corresponding author ; on behalf of the Let's Prevent Diabetes Team
- 关键词：Type 2 diabetes ; Pre-diabetes ; Prevention ; Lifestyle ; Clinical trial
- 刊名：Preventive Medicine
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：84
- 期：Complete
- 页码：48-56
- 全文大小：487 K
文摘
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To date there has been a dearth of evidence for T2DM prevention in a UK community setting.
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This is the first large scale RCT to evaluate the effect of a T2DM prevention intervention (Let's Prevent) in a UK community setting.
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This study showed a non-significant 25%–35% reduction in the progression to T2DM at 3 years with a number of improvements in secondary outcomes and health behaviours.
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Let's Prevent provides a model of T2DM prevention that can be directly implemented and commissioned within primary care or public health services using existing infrastructure for the delivery of structured education.
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Future research should focus on increasing uptake to screening and attendance at education sessions.