Ursodeoxycholic and deoxycholic acids: Differential effects on intestinal Ca2+ uptake, apoptosis and autophagy of rat intestine
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- 作者：Valeria A. Rodrí ; guez1 ; Marí ; a A. Rivoira1 ; Adriana del V. Pé ; rez ; Ana M. Marchionatti ; Nori G. Tolosa de Talamoni ; ntolosatalamoni@yahoo.com.ar" class="auth_mail" title="E-mail the corresponding author ; ntolosa@biomed.fcm.unc.edu.ar" class="auth_mail" title="E-mail the corresponding author
- 关键词：UDCA ; NaDOC ; Ca2+ uptake ; Apoptosis ; Autophagy ; NO
- 刊名：Archives of Biochemistry and Biophysics
- 出版年：2016
- 出版时间：1 February 2016
- 年：2016
- 卷：591
- 期：Complete
- 页码：28-34
- 全文大小：899 K
文摘
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NaDOC decreases and UDCA increases Ca2+ uptake by mature enterocytes. NaDOC triggers and UDCA decreases the apoptosis.
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NO content and iNOS protein are enhanced by NaDOC, which is avoided by UDCA.
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Autophagy is produced by NaDOC, which is also prevented by UDCA.