Pathogenicity/parasite burden of 4 L. major strains were compared in C57BL/6 mice.
The expressions of C57BL/6 cytokine gene induced by the 4 strains were evaluated.
Strain DA39 showed higher expression of Ifng and Il12 at week 8 post-infection.
The ratio of Ifng/Il4 mRNA expressions in DA39 was higher than the other strains.
DA39 appears as a suitable strain for leishmaniases vaccine studies.