Exposure to methylphenidate during peri-adolescence affects endocrine functioning and sexual behavior in female Long-Evans rats
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- 作者：Fay A. Guarracia ; ; Caroline Holifielda ; Jessica Morales-Valenzuelaa ; Kasera Greenea ; Jeanette Browna ; Rebecca Lopeza ; Christina Crandalla ; Nicole Gibbsa ; Rebekah Velaa ; Melissa Y. Delgadob ; Russell J. Frohardtc
- 关键词：Adolescence ; Locomotion ; Partner preference ; Psychomotor stimulants ; Ritalin ; Chronic ; Acute ; Sexual motivation
- 刊名：Pharmacology Biochemistry and Behavior
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：142
- 期：Complete
- 页码：36-41
- 全文大小：426 K
文摘
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Chronic methylphenidate during peri-adolescence has long lasting effects on female rats.
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Endocrine functioning is altered; puberty is delayed and estrous cyclicity is more irregular.
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Sexual behavior, when tested in adulthood, is affected.
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Sensitivity to male is increased during first sexual experiences.