- 作者：Eleonora Vanzi ; Mara Bruzzi ; Marta Bucciolini ; G.A. Pablo Cirrone ; Carlo Civinini ; Giacomo Cuttone ; Domenico Lo Presti ; Stefania Pallotta ; Cristina Pugliatti ; Nunzio R ; azzo ; Francesco Romano ; Monica Scaringella ; Valeria Sipala ; Concetta Stancampiano ; Cinzia Talamonti ; Margherita Zani
- 关键词：Proton Computed Tomography (PCT) ; Filtered backprojection (FBP) ; Tomographic image reconstruction ; Proton radiation therapy
- 刊名：Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
- 出版年：1 December, 2013
- 年：2013
- 卷：730
- 期：Complete
- 页码：184-190
- 全文大小：2766 K
The Filtered Back-Projection (FBP) algorithm was used to reconstruct projections of a phantom acquired with a 62 MeV proton beam. Image noise and spatial resolution were assessed for different parameters of the filter used, with and without selection strategies on proton directions.
A satisfactory image quality (0.88 mm resolution and 2.5% noise) was achieved even when the backprojection line was defined using only the line connecting the impact points on the second and third planes and all the data were used, irrespective of the proton direction and residual energy. Probably due to the specific detector-phantom arrangement used in this experiment and due to the substantial reduction of the number of useful events, cuts on proton directions did not increase the image resolution significantly.
The results confirm the good performances of the PRIMA scanner prototype. They also demonstrate that FBP can produce images of sufficient quality to be used for patient positioning and to initialize iterative pCT reconstruction methods.