Ceramic scaffolds with immobilized vancomycin-loaded poly(lactide-co-glycolide) microparticles for bone defects treatment

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• 作者：Łucja Rumian^a ; Hanna Tiainen^b ; Urszula Cibor^a ; Małgorzata Krok-Borkowicz^a ; Monika Brzychczy-Włoch^c ; Hå ; vard J. Haugen^b ; Elżbieta Pamuła^a ; ^{epamula@agh.edu.pl}
• 关键词：Porous biomaterials ; TiO2 scaffolds ; PLGA ; Vancomycin ; Antimicrobial activity
• 刊名：Materials Letters
• 出版年：2017
• 出版时间：1 March 2017
• 年：2017
• 卷：190
• 期：Complete
• 页码：67-70
• 全文大小：1226 K
• 卷排序：190

文摘

Cross-linked sodium alginate effectively immobilized vancomycin-loaded microparticles on TiO2 scaffolds. System assured required drug release. Antimicrobial activity of the proposed system against Staphylococcus spp. Cytocompatibility of the system in contact with osteoblast-like cells.