A five-gene expression signature to predict progression in T1G3 bladder cancer
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- 作者：Antoine G. van der Heijdena ; 1 ; Toine.vanderHeijden@radboudumc.nl" class="auth_mail" title="E-mail the corresponding author ; Lourdes Mengualb ; 1 ; lmengual@clinic.ub.es" class="auth_mail" title="E-mail the corresponding author ; Juan J. Lozanoc ; juanjo.lozano@Ciberehd.org" class="auth_mail" title="E-mail the corresponding author ; Mercedes Ingelmo-Torresb ; INGELMO@clinic.ub.es" class="auth_mail" title="E-mail the corresponding author ; Maria J. Ribalb ; mjribal@clinic.ub.es" class="auth_mail" title="E-mail the corresponding author ; Pedro L. Ferná ; ndezd ; PLFERNAN@clinic.ub.es" class="auth_mail" title="E-mail the corresponding author ; Egbert Oosterwijka ; Egbert.Oosterwijk@radboudumc.nl" class="auth_mail" title="E-mail the corresponding author ; Jack A. Schalkena ; Jack.Schalken@radboudumc.nl" class="auth_mail" title="E-mail the corresponding author ; Antonio Alcarazb ; ALCARAZ@clinic.ub.es" class="auth_mail" title="E-mail the corresponding author ; J. Alfred Witjesa ; Fred.Witjes@radboudumc.nl" class="auth_mail" title="E-mail the corresponding author
- 关键词：Biomarkers ; Bladder cancer ; Gene expression signature ; Prognosis ; Progressive disease
- 刊名：European Journal of Cancer
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：64
- 期：Complete
- 页码：127-136
- 全文大小：1826 K
文摘
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Markers for tumour progression in bladder cancer are studied.
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Progressive and non-progressive T1G3 bladder tumours show different gene expression patterns.
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A five-gene expression signature has been developed to identify T1G3 bladder cancer patients with a high risk of progression.