Vegfa signaling promotes zebrafish intestinal vasculature development through endothelial cell migration from the posterior cardinal vein
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- 作者：Andrew L. Koeniga ; andrew.koenig@cchmc.org" class="auth_mail" title="E-mail the corresponding author ; Kristina Baltrunaitea ; kristina.baltrunaite@cchmc.org" class="auth_mail" title="E-mail the corresponding author ; Neil I. Bowerb ; n.bower@imb.uq.edu.au" class="auth_mail" title="E-mail the corresponding author ; Andrea Rossic ; andrea.rossi@mpi-bn.mpg.de" class="auth_mail" title="E-mail the corresponding author ; Didier Y.R. Stainierc ; didier.stainier@mpi-bn.mpg.de" class="auth_mail" title="E-mail the corresponding author ; Benjamin M. Hoganb ; b.hogan@imb.uq.edu.au" class="auth_mail" title="E-mail the corresponding author ; Saulius Sumanasa ; saulius.sumanas@cchmc.org" class="auth_mail" title="E-mail the corresponding author
- 关键词：Zebrafish ; Vegf ; Intestinal ; Vascular endothelial ; Organ
- 刊名：Developmental Biology
- 出版年：2016
- 出版时间：1 March 2016
- 年：2016
- 卷：411
- 期：1
- 页码：115-127
- 全文大小：11742 K
文摘
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Zebrafish intestinal vasculature forms by a novel mechanism of angioblast migration.
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Angioblasts migrate from the cardinal vein to form intestinal vessels.
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Vegfaa provides a likely guidance signal for intestinal progenitor migration.
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Kdr and Kdrl have partially overlapping roles in intestinal vessel development.