Deep venomics of the Pseudonaja genus reveals inter- and intra-specific variation
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- 作者：Timothy Reeksa ; Vincent Lavergnea ; Kartik Sunagarb ; Alun Jonesa ; Eivind Undheima ; Nathan Dunstanc ; Bryan Frya ; d ; Paul F. Alewooda ; p.alewood@imb.uq.edu.au" class="auth_mail" title="E-mail the corresponding author
- 关键词：Venomics ; Venom gland transcriptome ; Proteome ; Snake toxins ; Glycopeptides ; Pseudonaja genus
- 刊名：Journal of Proteomics
- 出版年：2016
- 出版时间：5 February 2016
- 年：2016
- 卷：133
- 期：Complete
- 页码：20-32
- 全文大小：2220 K
文摘
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Comparison of venom gland transcriptomes and proteomes from Pseudonaja family
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Annotation of reads identified 5716 transcripts from 20 different toxin families
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Integration of specimen specific proteomes identified 65 isoforms
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Discovery of unique natriuretic peptides displaying O-linked trisaccharides
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Molecular evolutionary assessment highlights intra and inter-specific variation