Mechanisms for in-the-bag uveitis-glaucoma-hyphema syndrome
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| Figures/TablesFigures/Tables | ReferencesReferencesml version="1.0" encoding="UTF-8"?>We propose 2 mechanisms of uveitis-glaucoma-hyphema (UGH) syndrome in 2 patients with intracapsular or in-the-bag single-piece acrylic intraocular lenses (IOLs). In the first case, pseudophacodonesis secondary to zonular laxity from pseudoexfoliation syndrome caused chafing of the posterior iris by the square-edged haptic. In the second case, focal capsular fibrosis around the square-edged haptics combined with anteriorly rotated ciliary processes in plateau iris configuration caused points of chafing. Extensive capsular fibrosis of the haptic in both cases precluded IOL exchange. In the first case, a capsular tension ring redistributed zonular tension and reduced symptoms. In the second case, endoscopic cyclophotocoagulation relieved areas of chafing and resolved symptoms. In-the-bag square-edged haptics of single-piece acrylic IOLs are a potential source of iridociliary chafing in certain situations. The mechanisms observed here should be considered to promptly diagnose and treat UGH.

Financial Disclosure

Dr. Moroi receives clinical research funding from Merck & Co., Inc. and book royalties from Lippincott Williams & Wilkins. No other author has a financial or proprietary interest in any material or method mentioned.

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