Perturbation of metabonome of embryo/larvae zebrafish after exposure to fipronil

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• 作者：Lu Yan^b ; Chenxue Gong^a ; Xiaofeng Zhang^b ; Quan Zhang^b ; Meirong Zhao^b ; Cui Wang^a ; ^{wangcui198506@163.com}
• 关键词：Fipronil ; Zebrafish embryo ; Metabolomics ; Malformation
• 刊名：Environmental Toxicology and Pharmacology
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：48
• 期：Complete
• 页码：39-45
• 全文大小：1615 K
• 卷排序：48

文摘

Fipronil induced malformation to zebrafish embryo including uninflated swim bladder, and bent spine. 26 differential metabolites were identified after exposure to acute fipronil. Cholesterol and saturated fatty acid were changed by fipronil. Aminoacyl-tRNA biosynthesis and methane metabolism pathway were altered by fipronil.