Adenoid cystic carcinoma of the larynx presenting with unusual subglottic mass: Case report

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• 作者：Takashi Kashiwagi ; Hiroaki Kanaya ; ^{h-kanaya@dokkyomed.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Wataru Konno ; Kazutaka Goto ; Hideki Hirabayashi ; Shin-ichi Haruna
• 关键词：Adenoid cystic carcinoma ; Larynx ; Subglottic mass ; Fiberscopy ; Prolonged cough
• 刊名：Auris Nasus Larynx
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：43
• 期：5
• 页码：562-565
• 全文大小：2816 K

文摘

A 33-year-old woman presented with an unusual subglottic bulging mass accompanied by prolonged cough and wheeze. Laryngeal endoscopy revealed a bilateral, symmetrical mass immediately below the vocal cords with marked airway obstruction. Chronic subglottic laryngitis with inflammation or another condition such as amyloidosis was initially suspected. Cervicothoracic computed tomography revealed an obvious reduction of laryngeal caliber caused by an engulfing mass extending from just under the vocal cords to the cricoid ring, which was associated with thyroid, arytenoid, and cricoid cartilage destruction. Histopathological diagnosis of a biopsy specimen collected via a tracheotomy revealed that the lesion was a cT4aN0M0 adenoid cystic carcinoma (ACC) originating from the laryngeal minor salivary glands. The patient was treated by total laryngectomy with elective bilateral neck dissection under general anesthesia. Gross inspection of resected tissue confirmed yellowish-white, solid tumor mainly circumferentially encompassing the lumina of the cricoid ring. The histopathological findings confirmed typical ACC accompanied by a predominant cribriform appearance with no evidence of lymph node metastasis. The patient remains well and free of recurrence or metastasis. We herein describe laryngeal ACC and discuss radiological images and the surgical pathology.