Exclusion of participants based on substance use status: Findings from randomized controlled trials of treatments for PTSD

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• 作者：Robert F. Leeman^a ; ^b ; ^c ; ^{robert.leeman@ufl.edu} ; Kathryn Hefner^b ; ^c ; ^{kathryn.hefner@yale.edu} ; Tessa Frohe^a ; ^{tfrohe@ufl.edu} ; Adrian Murray^d ; ^{adrian.murray@va.gov} ; Robert A. Rosenheck^b ; ^c ; ^{robert.rosenheck@yale.edu} ; Bradley V. Watts^e ; ^f ; ^{bradley.watts@va.gov} ; Mehmet Sofuoglu^b ; ^c ; ^{mehmet.sofuoglu@yale.edu}
• 关键词：Substance use disorder ; Comorbidity ; Multimorbidity ; Pharmacotherapy ; Psychotherapy ; Alcohol ; Drug ; Clinical trial
• 刊名：Behaviour Research and Therapy
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：89
• 期：Complete
• 页码：33-40
• 全文大小：333 K
• 卷排序：89

文摘

Exclusion based on substance use was common in published RCTs for PTSD treatments. Many RCTs used restrictive criteria in terms of SUD diagnosis. Reporting of substance-related outcome findings was uncommon. Most findings reported suggest no disadvantage in PTSD treatment for those with SUD. No clear evidence exclusion criteria relates to PTSD outcome or participant dropout. There is no current evidence that PTSD treatment worsens comorbid SUD.