The ZnO-NRs/Au substrate is a promising candidate for developing mass-manufactured, low cost, sensitive, and high-throughput protein microarray platforms.
The large surface area of the ZnO-NRs nanoarrays and the plasmonic coupling effects of the Au nanofilm result in a significant fluorescence signal enhancement.
The cancer biomarker CEA is detected in a broad dynamic range of 100 pg mL−1 to 100 μg mL−1 with a limit of detection of 27 pg mL−1.