Lacosamide 300–400 mg/day was efficacious as a first or later add-on for POS.
37.5% of patients taking lacosamide as first add-on were seizure-free at 12 weeks.
14.9% of patients taking lacosamide as later add-on were seizure-free at 12 weeks.
Both patient groups reported improvements from Baseline in quality of life outcomes.
Lacosamide was well tolerated, with a good tolerability profile as a first add-on.