Polyoxygenated cyclohexene derivatives from Monanthotaxis congoensis

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• 作者：Courtney M. Starks ; ^{cstarks@sequoiasciences.com} ; Russell B. Williams ; Stephanie M. Rice ; Vanessa L. Norman ; Julie A. Lawrence ; Matt G. Goering ; Mark O&rsquo ; Neil-Johnson ; Jin-Feng Hu ; Gary R. Eldridge
• 关键词：Monanthotaxis congoensis ; Annonaceae ; Polyoxygenated cyclohexene ; Cytotoxicity
• 刊名：Phytochemistry
• 出版年：2012
• 出版时间：February, 2012
• 年：2012
• 卷：74
• 期：Complete
• 页码：185-189
• 全文大小：211 K

文摘

A phytochemical investigation of Monanthotaxis congoensis afforded eight polyoxygenated cyclohexenes as well as the known crotepoxide. Structures were determined using NMR, MS, and optical rotation analyses. One compound displayed moderate antiproliferative activity against NCI-H460 and M14 cancer cells.