Layer II of placental syncytiotrophoblasts expresses MDR1 and BCRP at the apical membrane in rodents
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- 作者：Tomoya Akashi<sup>asup> ; Tomohiro Nishimura<sup>asup> ; Yoshiya Takaki<sup>asup> ; Masaya Takahashi<sup>asup> ; Bo-Chul Shin<sup>bsup> ; Masatoshi Tomi<sup>asup><sup> ; sup><sup>tomi-ms@pha.keio.ac.jp" class="auth_mail" title="E-mail the corresponding authorsup> ; Emi Nakashima<sup>asup>
- 关键词：SynTI ; syncytiotrophoblast layer I ; SynT-II ; syncytiotrophoblast layer II ; MDR1 ; multidrug resistance protein 1 ; BCRP ; breast cancer resistance protein ; GLUT1 ; glucose transporter 1 ; Cx26 ; connexin 26
- 刊名：Reproductive Toxicology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：65
- 期：Complete
- 页码：375-381
- 全文大小：3759 K
文摘
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In rodents, MDR1 and BCRP are expressed in syncytiotrophoblast layer II.
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In layer II, MDR1 and BCRP are localized in the apical membrane.
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Layer II plays a defensive role in the machinery of the placental barrier.